What Your Stool Donation Estimate Actually Means

By DonorPayCalculator Updated January 2026 8 min read

Quick Answer

Your stool donation estimate represents potential earnings contingent on passing rigorous screening that rejects over 97% of applicants. Programs like GoodNature and OpenBiome have different pay structures and requirements. Your estimate assumes consistent daily or near-daily donations, which requires living near a collection facility and maintaining strict dietary and health standards throughout your donor period.

How Your Estimate Was Calculated

Stool donation calculators project earnings based on program selection, donation frequency, and published compensation rates. Understanding each factor helps you evaluate how achievable the estimate is for your circumstances.

Program-Specific Payment Rates

Different stool banking programs pay different amounts per sample. GoodNature typically pays $75-100 per donation with consistency bonuses. OpenBiome has historically paid $40-50 per donation. Human Microbes pays up to $500 per sample but accepts fewer than 0.5% of applicants. Your estimate reflects the program you selected and its current published rates.

Frequency Assumptions

Stool donation programs often encourage daily donations, 5-7 days per week. Your estimate multiplies per-donation pay by your stated frequency. Actual donation consistency depends on your digestive regularity, schedule flexibility, and proximity to collection facilities. Most donors average fewer donations than initially planned.

Bonus Structure Impact

Many programs offer quarterly consistency bonuses of $300-500 for donors who maintain regular schedules without gaps. Your estimate may include prorated bonus amounts. Missing donation windows or experiencing health-related pauses can forfeit these bonuses entirely.

Limits and Variables That Affect Your Earnings

Extremely Selective Screening

Stool donation has the lowest acceptance rate of any biological donation type. Programs screen for hundreds of health markers, dietary factors, medication use, travel history, and microbiome composition. Only 2-3% of applicants ultimately become active donors. Your estimate assumes you are among this small percentage.

Geographic Requirements

Unlike other donation types, stool samples must be delivered fresh, typically within 1-2 hours of production. This requires living very close to a collection facility. Programs operate from limited locations, primarily in major metropolitan areas. If you do not live nearby, donation is not feasible regardless of qualification.

Dietary and Lifestyle Restrictions

Active donors must maintain specific dietary patterns and avoid many common medications, including antibiotics, which result in multi-month suspensions. Travel restrictions, alcohol limits, and supplement prohibitions also apply. These ongoing requirements cause some qualified donors to voluntarily end participation.

FactorImpact on Estimate
Screening rejection (97%+)Eliminates all projected earnings
Geographic ineligibilityProgram not accessible
Antibiotic use3-6 month suspension, loss of bonuses
Consistency bonuses+$1,200-2,000 annually if maintained
Irregular schedule-30-50% of maximum earnings

Common Mistakes When Interpreting Your Estimate

Underestimating Rejection Likelihood

With acceptance rates under 3%, most people exploring stool donation will not qualify. Calculators cannot screen for microbiome quality, which is the primary qualification factor. Treat your estimate as highly conditional until you have passed all screening stages.

Ignoring Location Constraints

The fresh sample requirement makes stool donation uniquely location-dependent. If you do not already live within 30-45 minutes of an active collection facility, the logistics are typically prohibitive. Moving for donation purposes rarely makes financial sense.

Expecting Flexibility

High earners in stool donation maintain rigid routines, donating at consistent times daily. Vacation, illness, schedule conflicts, and dietary lapses all reduce earnings. Your estimate assumes optimal consistency that most donors do not achieve.

Comparing to Premium Program Rates

Human Microbes' $500 per donation rate appears in many discussions but represents an extremely rare opportunity. Fewer than 1 in 200 applicants qualify for premium programs. Standard program rates of $40-100 per donation are more realistic benchmarks.

Next Steps Based on Your Donation Estimate

  • Track visits: Log dates, bonuses, and payouts.
  • Prepare properly: Hydration and nutrition reduce deferrals.
  • Understand payouts: Fees and timing affect take-home pay.

Frequently Asked Questions

What makes stool donation screening so selective?

Programs test for hundreds of pathogens, assess microbiome diversity and composition, review extensive health histories, and evaluate lifestyle factors. The samples are used in medical treatments, requiring exceptional quality standards that most healthy people do not meet.

How long does the screening process take?

Initial screening takes 4-8 weeks including questionnaires, blood tests, stool sample analysis, and medical review. You do not receive compensation during screening. Many applicants are rejected at various stages throughout this process.

Can I improve my chances of qualifying?

Microbiome composition is largely determined by factors outside your control, including early life exposures and genetics. While healthy diet and lifestyle may help, there is no reliable way to ensure qualification. Apply if interested, but do not count on acceptance.

What happens if I need antibiotics while donating?

Antibiotic use typically requires a 3-6 month pause in donations while your microbiome recovers. This suspension eliminates consistency bonuses and significantly reduces annual earnings. Frequent antibiotic needs may result in program dismissal.

Are stool donation earnings taxable?

Stool donation compensation is considered taxable income. High-earning donors receive tax documentation and should plan for tax obligations on their earnings.

Recalculate Your Estimate

Adjust program selection or frequency assumptions to explore different scenarios.

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