GoodNature Stool Donation Program 2026: Complete Guide to Pay, Requirements & Locations

By Glen Meade Updated January 2026 16 min read
Modern medical research laboratory

Key Takeaways:

  • GoodNature pays donors $50-75 per donation, with potential earnings of $500-1,500/month
  • Only 3-5% of applicants qualify due to strict microbiome requirements
  • Donations help patients suffering from C. diff infections and other conditions
  • Currently operating in Massachusetts with potential expansion planned
  • Free comprehensive health screening valued at $1,500+ for all applicants

Stool donation has emerged as one of the most lucrative—and unusual—ways to earn money in 2026. Among the handful of programs accepting donors, GoodNature has established itself as a leading player in the field of fecal microbiota transplantation (FMT). If you've been searching for "GoodNature stool donation near me" or wondering how to qualify for paid poop donation, this comprehensive guide covers everything you need to know.

Unlike blood or plasma donation, stool donation has extremely strict requirements, with acceptance rates of just 3-5%. But for those who qualify, the rewards are substantial: regular income, free health monitoring, and the satisfaction of helping patients with life-threatening conditions.

What is GoodNature?

Scientific research and microbiome studies

GoodNature is a Massachusetts-based company that operates one of the premier stool donation and FMT (fecal microbiota transplantation) programs in the United States. Founded by microbiome researchers and physicians, GoodNature collects donations from rigorously screened "super donors" and prepares them for therapeutic use in treating patients with various gastrointestinal conditions.

The Science Behind Stool Donation

Your gut contains trillions of bacteria, viruses, and other microorganisms collectively known as the gut microbiome. A healthy, diverse microbiome is essential for digestion, immune function, and even mental health. When this balance is disrupted—often by antibiotics—harmful bacteria like Clostridioides difficile (C. diff) can take over, causing severe and sometimes fatal infections.

Fecal microbiota transplantation (FMT) involves transferring stool from a healthy donor to a patient's gastrointestinal tract, essentially "rebooting" their gut microbiome. FMT has shown cure rates of up to 90% for recurrent C. diff infections, compared to just 20-30% for antibiotic treatment alone.

Why GoodNature Matters

GoodNature operates under strict FDA guidelines and maintains some of the highest quality standards in the industry. Their donations are used by hospitals and gastroenterologists across the country to treat patients with:

How Much Does GoodNature Pay? (2026 Rates)

GoodNature offers competitive compensation that makes stool donation one of the highest-paying donation types per hour of time invested.

GoodNature Compensation Structure (2026):

  • Per Donation: $50-75 per sample
  • Weekly Potential: $150-300 (3-5 donations)
  • Monthly Potential: $500-1,500
  • Annual Potential: $6,000-18,000
  • Signup Bonus: Variable, check current promotions

Payment Details

Maximizing Your Earnings

The key to maximizing stool donation income is consistency. GoodNature rewards regular donors who maintain sample quality. Donors who donate 4-5 times weekly can realistically earn $1,000-1,500 monthly, making this a significant income stream.

Donor Requirements & Qualifications

Healthy lifestyle and diet concept

GoodNature has some of the strictest donor requirements in any donation field. Their goal is to identify "super donors" with exceptionally healthy, diverse microbiomes. Only about 3-5% of applicants ultimately qualify.

Basic Eligibility Requirements

RequirementGoodNature Standard
Age18-50 years old
BMI18.5-30 (healthy weight range)
General HealthExcellent overall health, no chronic conditions
GI HealthNo history of IBS, IBD, or other GI disorders
Antibiotic UseNo antibiotics in past 3-6 months
LocationWithin commuting distance of donation center

Automatic Disqualifiers

You Cannot Donate If You Have:

  • History of GI disorders (IBS, Crohn's, ulcerative colitis)
  • Recent antibiotic use (past 3-6 months)
  • Autoimmune diseases
  • Metabolic disorders (diabetes, thyroid issues)
  • Chronic infections (HIV, Hepatitis B/C)
  • Recent travel to high-risk regions
  • Regular use of certain medications
  • Obesity (BMI over 30)
  • History of drug use
  • Certain dietary restrictions or eating disorders

The "Super Donor" Profile

GoodNature is looking for individuals with exceptionally healthy microbiomes. The ideal donor:

Application Process: Step-by-Step

The GoodNature application process is thorough and multi-stage. Here's exactly what to expect:

Step 1: Online Pre-Screening (10-15 minutes)

Complete the initial questionnaire on GoodNature's website. This covers:

You'll typically hear back within 1-2 weeks if you pass pre-screening.

Step 2: Phone Interview (30-45 minutes)

A GoodNature coordinator conducts a detailed phone interview covering:

Step 3: Initial Stool Sample Submission

You'll receive a collection kit to provide an initial stool sample. This sample undergoes extensive testing including:

Step 4: Blood Testing & Physical

Candidates with qualifying stool samples proceed to comprehensive blood testing:

Step 5: Approval & Onboarding

Successful candidates receive approval and complete onboarding:

GoodNature Locations

Boston Massachusetts skyline

Currently, GoodNature operates primarily in Massachusetts, with their main facility in the Greater Boston area. However, they have various collection options:

Current Donation Options

On-Site Donation

Visit the GoodNature facility to provide samples. Best for donors living near Boston. Highest compensation rates.

At-Home Collection

For qualified donors in the Greater Boston area, at-home collection with pickup may be available.

Future Expansion Plans

GoodNature has indicated plans to expand to additional markets. Cities rumored to be under consideration include:

If you're not in the Boston area, consider applying anyway—you may be contacted when expansion reaches your region.

What to Expect as a GoodNature Donor

Understanding the donation experience helps you prepare for success as a stool donor.

The Daily Donation Routine

  1. Morning routine: Most donors provide samples in the morning when natural
  2. Collection: Use provided sterile collection kit
  3. Delivery: Drop off at facility or schedule pickup within 1-2 hours
  4. Processing: GoodNature processes samples immediately
  5. Quality check: Each sample tested before payment
  6. Payment: Credited to your account for approved samples

Time Commitment

Ongoing Requirements

Maintaining donor status requires ongoing compliance:

Health Benefits of Qualifying

Beyond compensation, GoodNature donors receive significant health benefits:

Free Comprehensive Screening

The initial screening process includes tests worth $1,500-2,000 or more:

Ongoing Health Monitoring

Active donors receive continuous health monitoring:

GoodNature vs Other Stool Donation Programs

How does GoodNature compare to other stool donation programs in 2026?

ProgramPay/DonationLocationsStatus
GoodNature$50-75MassachusettsActive
OpenBiome$40-50MassachusettsLimited
Seres TherapeuticsVariableClinical trial sitesResearch
Human Microbes$500+/sampleRemote/ShippingPremium

Why Choose GoodNature?

Tips for Qualifying as a GoodNature Donor

Healthy food and diet for gut health

With only 3-5% of applicants qualifying, you'll want to optimize your chances. Here's how:

Optimize Your Diet (Start 2-4 Weeks Before Applying)

Optimize Your Lifestyle

Consider Probiotics

While evidence is mixed on whether probiotics help with screening, many successful donors report taking high-quality probiotics with diverse strains for several weeks before their initial sample submission.

Frequently Asked Questions

Is GoodNature stool donation legitimate?

Yes, GoodNature is a legitimate, established stool bank operating under FDA guidelines. They supply FMT material to hospitals and gastroenterologists nationwide for treating C. diff infections and other conditions.

How often can I donate stool to GoodNature?

Active donors typically donate 3-5 times per week, depending on their natural schedule and sample quality. There's no "forced" frequency—you donate when you naturally need to have a bowel movement.

Why is the acceptance rate so low?

Stool donation has incredibly strict requirements because the donations are used therapeutically in sick patients. Any pathogens or unhealthy microbes in donor stool could harm recipients. The 3-5% acceptance rate reflects how rare truly healthy microbiomes are.

Can I donate if I take probiotics?

Generally yes, but disclose all supplements during screening. GoodNature wants donors with naturally healthy microbiomes, so heavy probiotic supplementation might be a concern. Modest probiotic use is typically acceptable.

What if I'm not near a GoodNature location?

Currently, GoodNature primarily serves the Greater Boston area. However, you can still apply to be notified of expansion. Alternative programs like Human Microbes accept remote donors who ship samples.

Is stool donation income taxable?

Yes, stool donation income is taxable as miscellaneous income. If you earn over $600 from GoodNature in a calendar year, you'll receive a 1099 form and should report the income on your tax return.

Can I still donate if I've taken antibiotics recently?

No. Recent antibiotic use is a disqualifier because antibiotics disrupt the microbiome. Most programs require 3-6 months without antibiotics before you can apply or resume donating.

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Conclusion: Is GoodNature Right for You?

GoodNature's stool donation program offers an exceptional opportunity for those who qualify. With potential earnings of $500-1,500 monthly, free comprehensive health screening, and the knowledge that you're helping save lives, it's one of the most rewarding donation opportunities available.

However, the strict requirements mean most applicants won't qualify. If you have excellent health, no GI issues, a diverse diet, and live near Boston, you have the best chance of acceptance. Even if you don't qualify, the free health screening provides valuable insights into your microbiome health.

Ready to apply? Visit GoodNature's website to complete the pre-screening questionnaire. With demand for FMT material growing and expansion plans in the works, 2026 is an excellent time to explore this unique opportunity.

Disclaimer: This guide provides general information about GoodNature's stool donation program as of January 2026. Requirements, compensation, and availability may change. Always verify current information directly with GoodNature.

Calculate Your Stool Donation Earnings

Use our calculator to estimate potential monthly and annual earnings from stool donation based on your location.