Sperm Donor Disqualifications: Complete List of What Gets You Rejected (2026)

By Glen Meade Updated March 2026 12 min read

Quick Stats:

  • Only 1 to 5 percent of sperm donor applicants are accepted
  • The most common reason for rejection is poor sperm quality — not health or lifestyle issues
  • Some disqualifications are permanent; others involve waiting periods
  • Requirements vary by bank, but most disqualifiers are consistent across the industry

Sperm banks reject more than 95 percent of applicants. If you want to avoid wasting time on applications you will not pass, this complete disqualification list tells you exactly what gets men rejected — organized by category so you can quickly assess your own situation before applying.

Physical Requirements: Height, Weight, and Age

Height

  • Under 5'7": disqualifying at all major accredited U.S. banks
  • Under 5'8": disqualifying at Xytex, New England Cryogenic, European Sperm Bank USA
  • Under 5'9": disqualifying at California Cryobank, Manhattan Cryobank, Cryos International (U.S.)

BMI and Weight

  • BMI above 28 to 30: most banks consider this a soft disqualifier; application reviewed cautiously
  • BMI above 35: generally disqualifying
  • BMI above 40 (morbid obesity): universally disqualifying
  • BMI below 18 (underweight): typically disqualifying; indicates potential health issues

Age

  • Under 18: universally disqualifying regardless of parental consent
  • Over 39: disqualifying at most banks (some accept up to 44)
  • Over 45: universally disqualifying at all major accredited banks

Sperm Quality Disqualifications

Poor sperm quality is the single most common reason men are rejected — more common than medical or lifestyle disqualifiers. Sperm banks require quality levels three to five times higher than the WHO minimum for clinical fertility.

  • Azoospermia: no sperm in ejaculate — permanent disqualification
  • Severe oligospermia: fewer than 15 million sperm per milliliter
  • Low total motility: fewer than 50 to 60 percent progressive motility
  • Poor morphology: less than 30 percent normal forms (banks require far above the WHO's 4 percent threshold)
  • Poor post-thaw survival: samples that lose too much motility after freezing — banks require at least 40 percent motility recovery
  • Low volume: ejaculate under 2.0 ml consistently
  • High white blood cells in sample: indicates active infection

Medical and Health Disqualifications

Chronic Conditions (Generally Permanent Disqualifiers)

  • Type 1 or Type 2 diabetes
  • Heart disease or any structural heart abnormality
  • Hypertension requiring medication
  • Kidney disease or dysfunction
  • Liver disease (including non-alcoholic fatty liver)
  • Autoimmune disorders (lupus, multiple sclerosis, rheumatoid arthritis, Crohn's disease)
  • Bleeding disorders (hemophilia, von Willebrand disease)
  • Severe or uncontrolled asthma
  • COPD or chronic lung disease
  • Thyroid disorders requiring ongoing medication
  • Epilepsy (current seizures or on anticonvulsant medication)
  • History of cancer (most types, especially before age 50)

Infectious Diseases (Permanent Disqualifiers)

  • HIV positive (any status)
  • Hepatitis B (current or past infection)
  • Hepatitis C (current or past infection)
  • HTLV-1 or HTLV-2 (human T-cell lymphotropic virus)
  • Creutzfeldt-Jakob disease or family history of it
  • Active syphilis (treated syphilis may be reviewed after documented cure and waiting period)

Infectious Diseases (Temporary Disqualifiers with Waiting Periods)

  • Zika virus exposure or travel to endemic areas: 6-month waiting period
  • Malaria: 12-month waiting period after treatment
  • Gonorrhea or chlamydia: 12 months after documented successful treatment
  • COVID-19 infection: 1 to 3 months depending on bank policy
  • Recent tattoos or piercings: 6 to 12 months
  • Recent blood transfusion: 12 months
  • Recent surgery with general anesthesia: typically 6 months

Genetic and Family Medical History Disqualifications

Note on Family History:

Banks review three generations of family history. A condition in your grandparents, parents, or siblings can disqualify you even if you are personally healthy. This is one area where applicants are frequently surprised.

Hereditary Genetic Conditions (Disqualifying in Donor or Close Family)

  • Huntington's disease
  • Cystic fibrosis (carrier status or affected)
  • Sickle cell disease or trait (some banks)
  • Duchenne or Becker muscular dystrophy
  • Fragile X syndrome
  • Polycystic kidney disease
  • Marfan syndrome
  • Neurofibromatosis (type 1 or 2)
  • Hereditary cancer syndromes: BRCA1/BRCA2 mutations, Lynch syndrome, familial adenomatous polyposis
  • Tay-Sachs disease (carrier in certain populations)
  • Spinal muscular atrophy (SMA)

Disqualifying Family History Patterns

  • Three or more first-degree relatives with the same cancer
  • Multiple relatives with heart disease before age 55
  • Alzheimer's disease in a parent or sibling
  • Multiple family members with schizophrenia or bipolar disorder
  • Unexplained infant deaths or multiple miscarriages in close relatives
  • Congenital birth defects in siblings or children
  • Multiple relatives with Type 1 diabetes

Mental Health Disqualifications

Permanent or Near-Permanent Disqualifiers

  • Schizophrenia or schizoaffective disorder
  • Bipolar I or II disorder
  • Major depressive disorder with current treatment or multiple episodes
  • Any personality disorder (borderline, antisocial, narcissistic)
  • Autism spectrum disorder (most banks)
  • History of suicide attempt or current suicidal ideation
  • Any history of psychiatric hospitalization
  • Current use of any psychiatric medication
  • Severe or recurrent panic disorder
  • OCD requiring ongoing medication or intensive treatment

Sometimes Reviewed Case-by-Case

  • Single episode of situational depression fully resolved without ongoing medication
  • ADHD managed without stimulant medication
  • Mild anxiety without medication history
  • Past therapy for life events (grief, adjustment disorder) with no current treatment

Substance Use Disqualifications

Current Use (Disqualifying)

  • Any illegal drug use, including marijuana in any form (even in legal states)
  • Tobacco products — cigarettes, vaping, chewing tobacco, cigars
  • Anabolic steroids
  • Alcohol abuse or dependency
  • Prescription drug misuse or abuse
  • Any intravenous drug use ever (permanent)

Waiting Periods After Cessation

  • Marijuana: 3 to 6 months clean
  • Tobacco: 6 to 12 months
  • Cocaine, amphetamines, MDMA: typically 1 to 2 years
  • Opioids (non-IV): 1 to 3 years depending on history
  • Alcohol abuse (not dependency): 12 months of documented sobriety

Sexual History and Behavior Disqualifications

  • HIV positive status: permanent disqualification
  • Men who have sex with men (MSM) in the past 3 to 5 years: many banks still follow FDA-derived deferral policies, though this is evolving
  • Sex work or pornography industry participation
  • Multiple concurrent sexual partners with unprotected sex (assessed by risk level)
  • Active untreated sexually transmitted infection

Medication Disqualifications

  • All psychiatric medications (SSRIs, SNRIs, antipsychotics, mood stabilizers, benzodiazepines)
  • Finasteride (Propecia, Proscar) — hair loss and prostate treatment
  • Isotretinoin (Accutane) — acne treatment; disqualifying while on it; waiting period after stopping
  • Testosterone replacement therapy or anabolic hormones
  • Immunosuppressants (for autoimmune conditions or organ transplant)
  • Chemotherapy agents (past or current)
  • Opioid pain medications (chronic use)
  • Blood pressure medications (most types; indicates hypertension which itself disqualifies)
  • Anticoagulants (warfarin, rivaroxaban, etc.) — indicates underlying clotting disorder

Criminal History Disqualifications

  • Any violent felony conviction: permanent disqualification
  • Sexual offenses of any kind: permanent disqualification
  • Domestic violence history: disqualifying
  • Child abuse or neglect findings: disqualifying
  • Current probation or parole: disqualifying
  • Drug trafficking or distribution convictions: disqualifying
  • Minor misdemeanors (traffic violations, petty theft more than 5 years ago): sometimes reviewed case-by-case

Travel and Geographic Disqualifications

  • Born in or lived in the United Kingdom or France between 1980 and 1996 for a cumulative three months or more: permanent disqualification due to variant Creutzfeldt-Jakob disease risk from mad cow disease outbreak
  • Received a blood transfusion in the UK between 1980 and 2001
  • Travel to Zika-endemic areas: 6-month waiting period
  • Travel to malaria-endemic areas: 12-month waiting period
  • Military service in certain high-risk zones: evaluated by specific period and location

Lifestyle and Logistical Disqualifications

  • Living more than 45 to 60 minutes from the sperm bank (most banks require proximity for regular donations)
  • Planning to move within six months
  • Unable to commit to donating one to three times per week for six to twelve months
  • No legal authorization to receive compensation in the United States (tourists, expired visas)
  • Already at maximum donor offspring limit for a bank (if transferring between banks)

The Most Commonly Overlooked Disqualifier:

Sperm quality. The majority of men who pass the initial screening — healthy, educated, tall enough — still get rejected because their sperm does not survive the freeze-thaw cycle at the required quality level. This is biological and cannot be changed through application strategy. It is also why banks typically ask for a trial sample early in the process before investing in full medical screening.

Conclusion

The scope of sperm donor disqualifications is broad, and most men who apply will not pass. That is not a personal failing — it is a function of how demanding the process is designed to be in order to protect recipient families and their children.

If you have reviewed this list and believe you are free of hard disqualifiers, your next step is choosing the right bank, submitting an initial application, and completing a trial semen analysis. The sperm quality test will tell you quickly whether the rest of the process is worth pursuing.

Estimate Your Earning Potential

If you believe you qualify, use our calculator to see what you could realistically earn based on your qualifications and location.

Frequently Asked Questions

What is the most common reason for sperm donor disqualification?

Poor sperm quality is the single most common reason men are rejected — more common than any medical or lifestyle disqualifier. Sperm banks require quality levels three to five times higher than the WHO minimum for clinical fertility, and most samples must also survive the freeze-thaw cycle at high motility levels.

Can you reapply to a sperm bank after being rejected?

It depends on the reason for rejection. If you were disqualified for a temporary condition — such as a recent tattoo, short-term medication use, or a treatable STI — you can typically reapply after the waiting period has passed. Permanent disqualifications like genetic conditions, HIV, or hepatitis cannot be reconsidered.

Do all sperm banks have the same disqualification criteria?

Most major banks follow similar core disqualifiers, but there are meaningful differences in areas like height minimums (5'7" to 5'9"), tattoo waiting periods (6 to 12 months), mental health evaluation flexibility, and medication policies. It is worth researching multiple banks before applying.

Can you be disqualified for family medical history alone?

Yes. Banks review three generations of family history. Conditions like Huntington's disease, cystic fibrosis, hereditary cancer syndromes, schizophrenia, or bipolar disorder in your parents, siblings, or grandparents can disqualify you even if you are personally healthy and unaffected.

Is being overweight a disqualifier for sperm donation?

It can be. A BMI above 28 to 30 is considered a soft disqualifier at most banks and your application will be reviewed cautiously. A BMI above 35 is generally disqualifying, and a BMI above 40 (morbid obesity) is universally disqualifying across all major accredited banks.

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